Trametes versicolor

🧭 Description & Habitat

A common bracket fungus with fan-shaped, concentric zones of brown, tan, white, and blue, resembling a turkey’s tail. Found worldwide on decaying hardwood logs and stumps, especially in moist, shaded forests. Grows in overlapping shelf-like clusters and is known for its tough, leathery texture.

📜 History & Ethnobotany

Used for centuries in Traditional Chinese Medicine (as Yun Zhi) and in Japanese Kampo medicine (as Kawaratake). Traditionally used to boost vitality, support the immune system, and as an adjunct in cancer therapy. Gained widespread interest in the West after studies highlighted its potential anticancer and immunomodulating properties.

🔬 Phytochemicals

Rich in bioactive compounds:

Polysaccharide-K (PSK or Krestin) – Immunostimulant used in Japanese oncology

Polysaccharide-Peptide (PSP) – Immune enhancer studied in China

Beta-glucans – Stimulate immune response

Phenols & flavonoids – Antioxidant and anti-inflammatory

Terpenoids – Potential anticancer effects

⚕️ Medicinal Benefits

Immune Modulation: Enhances activity of natural killer (NK) cells, macrophages, and T-cells

Cancer Support: PSK and PSP used as adjuncts in chemotherapy in Japan and China

Antiviral Properties: Shown activity against HPV, HSV, and influenza in lab settings

Gut Health: Supports a healthy microbiome by
acting as a prebiotic

Liver Protection: Early studies suggest
hepatoprotective benefits

🍽️ Uses & Forms

Not typically consumed fresh due to tough texture. Commonly taken as decoction (tea), powder, capsule,
or tincture. Often included in immune support blends
or mushroom complex supplements.

🚫 Risks & Side Effects

Generally well tolerated. Mild side effects may include bloating, dark stools, or allergic reaction. People undergoing immunosuppressive therapy (e.g., organ transplants) should avoid use. Not enough safety data
for use during pregnancy or breastfeeding.